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P.G. KOSTYUK (2020) 'CALCIUM SIGNALING: KYIV HISTORY' in O.A. Krishtal, E.A. Lukyanetz (Eds.), ESSAYS ON NEUROPHYSIOLOGY BY PLATON KOSTYUK AND HIS STUDENTS, AKADEMPERIODYKA, pp. 21-25

CALCIUM SIGNALING: KYIV HISTORY

P.G. KOSTYUK

    Bogomoletz Institute of physiology NAS of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/biph.books.EssNeur.021


Abstract

The idea of a particular role of calcium ions in the maintenance of basic functional properties of living cells was expressed almost a century ago. As it has been noticed by the pioneering observations of Ringer (1873) and Loeb (1906), a defi - nite relation between monovalent (sodium) and divalent (calcium) in the external medium is necessary for the execution of active cellular reactions. Th e way to the understanding of the mechanisms of this crucial role of Ca ions has been long and complicated, and our group has quite eff ectively participated in it, and here I would like to remind briefl y how it happened.

Keywords: Calcium ions, electrophysiology, calcium channels, intracellular perfusion, mitochondria, synaptic transmission, aging neurons, Alzheimer’s disease

Full text: (PDF, in English)

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