This study investigates the electrophysiological properties of calcium and sodium currents in the somatic membrane of rat dorsal root ganglion neurons. Using isolated neurons perfused with potassium-free solutions containing cyclic adenosine monophosphate (cAMP), adenosine triphosphate (ATP), and magnesium ions (Mg²⁺), we demonstrate the stabilization and restoration of inward calcium currents. The kinetics of calcium currents follow a modified Hodgkin-Huxley model, with activation dependent on extracellular calcium concentration and significantly enhanced by barium (Ba²⁺). Additionally, a tetrodotoxin (TTX)-resistant sodium current was identified, exhibiting characteristics of both sodium-selective and calcium-gated channels. These findings suggest that intracellular cyclic nucleotide metabolism plays a crucial role in maintaining the normal function of voltage-gated calcium channels in sensory neurons.