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O.V. HURA, O.M. NESYN, Yu.P. LYMANSKY (2020) 'SUPPRESSION OF PAIN IN MICE BY ANALGINUM AND MICROWAVE IRRADIATION OF ACUPUNCTURE POINT' in O.A. Krishtal, E.A. Lukyanetz (Eds.), ESSAYS ON NEUROPHYSIOLOGY BY PLATON KOSTYUK AND HIS STUDENTS, AKADEMPERIODYKA, pp. 95-101

SUPPRESSION OF PAIN IN MICE BY ANALGINUM AND MICROWAVE IRRADIATION OF ACUPUNCTURE POINT

O.V. HURA, O.M. NESYN, Yu.P. LYMANSKY

    Bogomoletz Institute of physiology NAS of Ukraine, Kyiv, Ukraine
DOI: https://doi.org/10.15407/biph.books.EssNeur.095


Abstract

Analgesic remedies are considered as the main tools against pain. Non-narcotic analgesic Analginum (Metamizol, Dypirone) is used widely as an over-the-counter drug (Ruiz et al., 2007). Using this drug, especially for a long time, frequently induces undesirable side e슏 ects: aplastic anemia, agranulocytosis (Hedenmalm et al., 2002), allergic reactions (Molto et al., 2004), and interstitial nephritis (Whelton, 2000). Hence, alternative methods of analgesia are in demand. One of such approaches is using low-intensity (below 10–3 W/ cm2) electromagnetic 긔 elds (EMF) of the microwave range.

Keywords: Analgesia, non-narcotic analgesics, metamizole, Analginum, opioid system, serotonergic system, pain suppression, acupuncture point, microwave irradiation, low-intensity electromagnetic fields, antinociceptive effects, pain management alternatives, visceral pain, somatic pain, drug synergy, noninvasive pain relief.

Full text: (PDF, in English)

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